{"id":699,"date":"2025-07-20T09:30:22","date_gmt":"2025-07-20T00:30:22","guid":{"rendered":"https:\/\/cocorokaradamegulu.com\/?p=699"},"modified":"2026-04-28T09:17:17","modified_gmt":"2026-04-28T00:17:17","slug":"drug-metabolism-excretion","status":"publish","type":"post","link":"https:\/\/cocorokaradamegulu.com\/?p=699","title":{"rendered":"\u4ee3\u8b1d\u30fb\u6392\u6cc4\u30fb\u8840\u4e2d\u6fc3\u5ea6\uff5c\u85ac\u304c\u4f53\u5185\u3067\u305f\u3069\u308b\u30d7\u30ed\u30bb\u30b9"},"content":{"rendered":"\n<p>\u300c\u540c\u3058\u85ac\u3092\u98f2\u3093\u3067\u3082\u4eba\u306b\u3088\u3063\u3066\u52b9\u304d\u65b9\u304c\u9055\u3046\u300d\u300c\u809d\u81d3\u3084\u814e\u81d3\u304c\u60aa\u3044\u3068\u85ac\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u300d\u2014\u2014\u305d\u306e\u7406\u7531\u306f\u3001\u85ac\u304c\u4f53\u5185\u3067\u305f\u3069\u308b\u30d7\u30ed\u30bb\u30b9\u3068\u6df1\u304f\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u3053\u306e\u8a18\u4e8b\u3067\u306f\u767b\u9332\u8ca9\u58f2\u8005\u8a66\u9a13\u306e\u5185\u5bb9\u3092\u30d9\u30fc\u30b9\u306b\u3001\u85ac\u306e\u4ee3\u8b1d\u30fb\u6392\u6cc4\u30fb\u8840\u4e2d\u6fc3\u5ea6\u306e\u3057\u304f\u307f\u3092\u6574\u7406\u3057\u307e\u3057\u305f\u3002\u8a66\u9a13\u3092\u53d7\u3051\u306a\u3044\u65b9\u306b\u3082\u3001\u85ac\u306e\u52b9\u679c\u3084\u526f\u4f5c\u7528\u3092\u6b63\u3057\u304f\u7406\u89e3\u3059\u308b\u305f\u3081\u306b\u5f79\u7acb\u3066\u3066\u3044\u305f\u3060\u3051\u308b\u5185\u5bb9\u3067\u3059\u3002<\/p>\n\n\n\n\n\n\n<figure class=\"wp-block-audio\"><audio controls src=\"https:\/\/cocorokaradamegulu.com\/wp-content\/uploads\/2025\/07\/\u4ee3\u8b1d\u30fb\u6392\u6cc4\u30fb\u8840\u4e2d\u6fc3\u5ea6.wav\"><\/audio><\/figure>\n\n\n\n<h2 id=\"rtoc-1\"  class=\"wp-block-heading jinr-heading d--bold\">1. \u85ac\u306e\u4ee3\u8b1d\u3068\u306f<\/h2>\n\n\n<p>\u4ee3\u8b1d\u3068\u306f\u3001\u85ac\u304c\u4f53\u5185\u3067\u5316\u5b66\u7684\u306b\u5909\u5316\u3059\u308b\u3053\u3068\u3067\u3059\u3002\u4f53\u304c\u7570\u7269\u3068\u5224\u65ad\u3057\u305f\u3082\u306e\u3092\u89e3\u6bd2\u3057\u3001\u6392\u6cc4\u3055\u308c\u3084\u3059\u3044\u5f62\u306b\u5909\u5316\u3055\u305b\u307e\u3059\u3002<\/p>\n\n\n<ul class=\"wp-block-list jinr-list\">\n<li>\u4ee3\u8b1d\u306b\u3088\u3063\u3066\u4f5c\u7528\u304c\u5931\u308f\u308c\u308b\uff08\u4e0d\u6d3b\u6027\u5316\uff09\u3053\u3068\u3082\u3042\u308b<\/li>\n\n\n\n<li>\u9006\u306b\u4ee3\u8b1d\u306b\u3088\u3063\u3066\u6d3b\u6027\u3092\u6301\u3064\u5225\u306e\u7269\u8cea\u306b\u5909\u308f\u308b\u3053\u3068\u3082\u3042\u308b<\/li>\n\n\n\n<li>\u3053\u306e\u4ed5\u7d44\u307f\u3092\u5229\u7528\u3057\u3066\u85ac\u306e\u52b9\u304b\u305b\u65b9\u3092\u8a2d\u8a08\u3057\u3066\u3044\u308b\u85ac\u3082\u3042\u308b<\/li>\n<\/ul>\n\n\n<p>\u4ee3\u8b1d\u306f\u4e3b\u306b<strong>\u809d\u81d3<\/strong>\u3067\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n<h2 id=\"rtoc-2\"  class=\"wp-block-heading jinr-heading d--bold\">2. \u85ac\u306e\u6392\u6cc4\u3068\u306f<\/h2>\n\n\n<p>\u4ee3\u8b1d\u3055\u308c\u305f\u85ac\uff08\u4ee3\u8b1d\u7269\uff09\u306f\u3001\u4f53\u5916\u3078\u6392\u51fa\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n<h3 id=\"rtoc-3\"  class=\"wp-block-heading jinr-heading d--bold\">\u4e3b\u306a\u6392\u6cc4\u7d4c\u8def<\/h3>\n\n\n\n<ul class=\"wp-block-list jinr-list\">\n<li><strong>\u814e\u81d3 \u2192 \u5c3f\u4e2d\u3078\u6392\u6cc4<\/strong>\uff08\u4e3b\u7d4c\u8def\uff09<\/li>\n\n\n\n<li><strong>\u809d\u81d3 \u2192 \u80c6\u6c41\u4e2d\u3078\u6392\u6cc4<\/strong>\uff08\u6d88\u5316\u7ba1\u3092\u901a\u3063\u3066\u4fbf\u4e2d\u306b\uff09<\/li>\n\n\n\n<li><strong>\u80ba \u2192 \u547c\u6c17\u4e2d\u306b\u6392\u51fa<\/strong>\uff08\u63ee\u767a\u6027\u306e\u85ac\uff09<\/li>\n\n\n\n<li><strong>\u6c57\u30fb\u6bcd\u4e73\u4e2d\u3078\u306e\u79fb\u884c<\/strong>\u3082\u3042\u308a\uff08\u7279\u306b\u4e73\u5150\u306b\u6ce8\u610f\uff09<\/li>\n<\/ul>\n\n\n\n<h3 id=\"rtoc-4\"  class=\"wp-block-heading jinr-heading d--bold\">\u809d\u6a5f\u80fd\u30fb\u814e\u6a5f\u80fd\u304c\u4f4e\u3044\u5834\u5408\u306e\u6ce8\u610f<\/h3>\n\n\n\n<ul class=\"wp-block-list jinr-list\">\n<li><strong>\u809d\u6a5f\u80fd\u304c\u4f4e\u3044\u4eba<\/strong>\uff1a\u4ee3\u8b1d\u3057\u3066\u7121\u6bd2\u5316\u3055\u308c\u308b\u306f\u305a\u306e\u85ac\u304c\u6b8b\u7559\u3057\u3066\u526f\u4f5c\u7528\u306b\u3064\u306a\u304c\u3063\u305f\u308a\u3001\u4ee3\u8b1d\u5f8c\u306b\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u306f\u305a\u306e\u85ac\u304c\u52b9\u304d\u306b\u304f\u304f\u306a\u308b\u3053\u3068\u304c\u3042\u308b<\/li>\n\n\n\n<li><strong>\u814e\u6a5f\u80fd\u304c\u4f4e\u3044\u4eba<\/strong>\uff1a\u6392\u6cc4\u306e\u51fa\u53e3\u304c\u8a70\u307e\u3063\u3066\u3044\u308b\u3088\u3046\u306a\u72b6\u614b\u3067\u3001\u85ac\u304c\u4f53\u5185\u306b\u84c4\u7a4d\u3057\u3066\u526f\u4f5c\u7528\u306b\u3064\u306a\u304c\u3063\u305f\u308a\u3001\u52b9\u679c\u306e\u30b3\u30f3\u30c8\u30ed\u30fc\u30eb\u304c\u96e3\u3057\u304f\u306a\u308b\u3002\u814e\u81d3\u3078\u306e\u8ca0\u62c5\u3082\u5897\u3048\u308b<\/li>\n<\/ul>\n\n\n\n<h2 id=\"rtoc-5\"  class=\"wp-block-heading jinr-heading d--bold\">3. \u809d\u521d\u56de\u901a\u904e\u52b9\u679c<\/h2>\n\n\n\n<p>\u53e3\u304b\u3089\u98f2\u3093\u3060\u85ac\u306f\u6d88\u5316\u7ba1\u3067\u5438\u53ce\u3055\u308c\u305f\u5f8c\u3001\u9580\u8108\u3092\u901a\u3063\u3066\u809d\u81d3\u3078\u904b\u3070\u308c\u307e\u3059\u3002\u3053\u306e\u3068\u304d\u809d\u81d3\u306e\u9175\u7d20\u306b\u3088\u3063\u3066\u4ee3\u8b1d\u3055\u308c\u308b\u3068\u3001\u5168\u8eab\u306b\u5c4a\u304f\u6709\u52b9\u6210\u5206\u304c\u6e1b\u3063\u3066\u3057\u307e\u3044\u307e\u3059\u3002\u3053\u308c\u3092<strong>\u809d\u521d\u56de\u901a\u904e\u52b9\u679c\uff08first-pass effect\uff09<\/strong>\u3068\u3044\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list jinr-list\">\n<li>\u809d\u6a5f\u80fd\u304c\u4f4e\u3044\u4eba\u3067\u306f\u4ee3\u8b1d\u304c\u3046\u307e\u304f\u3044\u304b\u305a\u3001\u672a\u4ee3\u8b1d\u6210\u5206\u304c\u591a\u304f\u6b8b\u308b<\/li>\n\n\n\n<li>\u305d\u306e\u7d50\u679c\u3001<strong>\u526f\u4f5c\u7528\u304c\u51fa\u3084\u3059\u304f\u306a\u308b<\/strong>\u30ea\u30b9\u30af\u304c\u3042\u308b<\/li>\n<\/ul>\n\n\n\n<h2 id=\"rtoc-6\"  class=\"wp-block-heading jinr-heading d--bold\">4. \u5faa\u74b0\u8840\u6db2\u4e2d\u3067\u306e\u85ac\u306e\u50cd\u304d<\/h2>\n\n\n\n<p>\u5438\u53ce\u30fb\u4ee3\u8b1d\u3092\u7d4c\u305f\u6709\u52b9\u6210\u5206\u306f\u8840\u6db2\u4e2d\u3078\u79fb\u52d5\u3057\u3001\u4f53\u5185\u306e\u6a19\u7684\uff08\u30bf\u30fc\u30b2\u30c3\u30c8\uff09\u7d30\u80de\u306b\u5c4a\u3044\u3066\u4f5c\u7528\u3092\u767a\u63ee\u3057\u307e\u3059\u3002<\/p>\n\n\n\n<ul class=\"wp-block-list jinr-list\">\n<li>\u8840\u6f3f\u4e2d\u306e\u30bf\u30f3\u30d1\u30af\u8cea\uff08\u30a2\u30eb\u30d6\u30df\u30f3\u306a\u3069\uff09\u3068\u7d50\u5408\u3057\u306a\u304c\u3089\u904b\u3070\u308c\u308b<\/li>\n\n\n\n<li>\u53d7\u5bb9\u4f53\u30fb\u9175\u7d20\u30fb\u8f38\u9001\u4f53\u306b\u304f\u3063\u3064\u3044\u3066\u7d30\u80de\u5185\u3067\u52b9\u679c\u3092\u51fa\u3059<\/li>\n<\/ul>\n\n\n\n<h2 id=\"rtoc-7\"  class=\"wp-block-heading jinr-heading d--bold\">5. \u8840\u4e2d\u6fc3\u5ea6\u3068\u6709\u52b9\u57df<\/h2>\n\n\n\n<p>\u8840\u4e2d\u6fc3\u5ea6\u3068\u306f\u3001\u8840\u6db2\u4e2d\u306b\u85ac\u304c\u3069\u308c\u3060\u3051\u6eb6\u3051\u3066\u3044\u308b\u304b\u3092\u793a\u3059\u6fc3\u5ea6\u306e\u3053\u3068\u3067\u3059\u3002\u85ac\u306e\u52b9\u679c\u3084\u526f\u4f5c\u7528\u306f\u3001\u3053\u306e\u8840\u4e2d\u6fc3\u5ea6\u306b\u5927\u304d\u304f\u5f71\u97ff\u3055\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u8840\u4e2d\u6fc3\u5ea6\u306e\u72b6\u614b<\/th><th>\u7d50\u679c<\/th><\/tr><\/thead><tbody><tr><td>\u6700\u4f4e\u6709\u52b9\u6fc3\u5ea6\u3088\u308a<strong>\u4f4e\u3044<\/strong><\/td><td>\u52b9\u679c\u304c\u51fa\u306a\u3044<\/td><\/tr><tr><td><strong>\u6709\u52b9\u57df\uff08\u6cbb\u7642\u57df\uff09\u5185<\/strong><\/td><td>\u5b89\u5168\u304b\u3064\u52b9\u679c\u7684<\/td><\/tr><tr><td><strong>\u4e2d\u6bd2\u57df\uff08\u5371\u967a\u57df\uff09<\/strong>\u306b\u9054\u3059\u308b<\/td><td>\u526f\u4f5c\u7528\u30fb\u6bd2\u6027\u304c\u51fa\u3084\u3059\u304f\u306a\u308b<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 id=\"rtoc-8\"  class=\"wp-block-heading jinr-heading d--bold\">6. \u91cd\u8981\u7528\u8a9e\u306e\u307e\u3068\u3081<\/h2>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><th>\u7528\u8a9e<\/th><th>\u610f\u5473<\/th><\/tr><\/thead><tbody><tr><td><strong>\u4ee3\u8b1d<\/strong><\/td><td>\u4f53\u5185\u3067\u5316\u5b66\u7684\u306b\u85ac\u3092\u5909\u5316\u3055\u305b\u308b\u3053\u3068<\/td><\/tr><tr><td><strong>\u6392\u6cc4<\/strong><\/td><td>\u85ac\u3084\u4ee3\u8b1d\u7269\u3092\u4f53\u5916\u3078\u51fa\u3059\u3053\u3068<\/td><\/tr><tr><td><strong>\u809d\u521d\u56de\u901a\u904e\u52b9\u679c<\/strong><\/td><td>\u809d\u81d3\u3067\u306e\u4ee3\u8b1d\u306b\u3088\u308a\u85ac\u306e\u6709\u52b9\u6210\u5206\u304c\u6e1b\u308b\u3053\u3068<\/td><\/tr><tr><td><strong>\u8840\u4e2d\u6fc3\u5ea6<\/strong><\/td><td>\u8840\u6db2\u4e2d\u306b\u6eb6\u3051\u3066\u3044\u308b\u85ac\u306e\u6fc3\u5ea6<\/td><\/tr><tr><td><strong>\u6709\u52b9\u57df\uff08\u6cbb\u7642\u57df\uff09<\/strong><\/td><td>\u5b89\u5168\u306b\u85ac\u306e\u52b9\u679c\u304c\u51fa\u308b\u8840\u4e2d\u6fc3\u5ea6\u306e\u7bc4\u56f2<\/td><\/tr><tr><td><strong>\u4e2d\u6bd2\u57df\uff08\u5371\u967a\u57df\uff09<\/strong><\/td><td>\u526f\u4f5c\u7528\u3084\u6bd2\u6027\u304c\u51fa\u3084\u3059\u304f\u306a\u308b\u6fc3\u5ea6\u7bc4\u56f2<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 id=\"rtoc-9\"  class=\"wp-block-heading jinr-heading d--bold\">\u8a66\u9a13\u3067\u62bc\u3055\u3048\u308b\u30ad\u30fc\u30ef\u30fc\u30c9\uff08\u76f4\u524d\u30c1\u30a7\u30c3\u30af\u7528\uff09<\/h2>\n\n\n\n<h3 id=\"rtoc-10\"  class=\"wp-block-heading jinr-heading d--bold\">\u4ee3\u8b1d\u306e\u4e3b\u306a\u5834\u6240<\/h3>\n\n\n\n<p>\u2192 \u809d\u81d3<\/p>\n\n\n\n<h3 id=\"rtoc-11\"  class=\"wp-block-heading jinr-heading d--bold\">\u6392\u6cc4\u306e\u4e3b\u7d4c\u8def<\/h3>\n\n\n\n<p>\u2192 \u814e\u81d3\uff08\u5c3f\u4e2d\uff09\u3002\u4ed6\u306b\u80c6\u6c41\u30fb\u547c\u6c17\u30fb\u6c57\u30fb\u6bcd\u4e73\u306a\u3069<\/p>\n\n\n\n<h3 id=\"rtoc-12\"  class=\"wp-block-heading jinr-heading d--bold\">\u809d\u6a5f\u80fd\u304c\u4f4e\u3044\u5834\u5408<\/h3>\n\n\n\n<p>\u2192 \u85ac\u304c\u6b8b\u7559\u3057\u3066\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u5897\u3001\u307e\u305f\u306f\u4ee3\u8b1d\u5f8c\u306b\u52b9\u679c\u3092\u767a\u63ee\u3059\u308b\u85ac\u304c\u52b9\u304d\u306b\u304f\u304f\u306a\u308b<\/p>\n\n\n\n<h3 id=\"rtoc-13\"  class=\"wp-block-heading jinr-heading d--bold\">\u814e\u6a5f\u80fd\u304c\u4f4e\u3044\u5834\u5408<\/h3>\n\n\n\n<p>\u2192 \u85ac\u304c\u84c4\u7a4d\u3057\u3066\u526f\u4f5c\u7528\u30ea\u30b9\u30af\u5897\u3002\u814e\u81d3\u3078\u306e\u8ca0\u62c5\u3082\u5897\u3048\u308b<\/p>\n\n\n\n<h3 id=\"rtoc-14\"  class=\"wp-block-heading jinr-heading d--bold\">\u809d\u521d\u56de\u901a\u904e\u52b9\u679c<\/h3>\n\n\n\n<p>\u2192 \u7d4c\u53e3\u85ac\u304c\u809d\u81d3\u3067\u4ee3\u8b1d\u3055\u308c\u3066\u5168\u8eab\u306b\u5c4a\u304f\u6210\u5206\u304c\u6e1b\u308b\u73fe\u8c61<\/p>\n\n\n\n<h3 id=\"rtoc-15\"  class=\"wp-block-heading jinr-heading d--bold\">\u8840\u4e2d\u6fc3\u5ea6\u306e3\u6bb5\u968e<\/h3>\n\n\n\n<p>\u2192 \u6700\u4f4e\u6709\u52b9\u6fc3\u5ea6\u4ee5\u4e0b\uff08\u7121\u52b9\uff09\u30fb\u6709\u52b9\u57df\uff08\u5b89\u5168\u30fb\u6709\u52b9\uff09\u30fb\u4e2d\u6bd2\u57df\uff08\u526f\u4f5c\u7528\u30fb\u6bd2\u6027\uff09<\/p>\n\n\n\n<h2 id=\"rtoc-16\"  class=\"wp-block-heading jinr-heading d--bold\">\u53c2\u8003\u8cc7\u6599<\/h2>\n\n\n\n<ul class=\"wp-block-list jinr-list\">\n<li><a href=\"https:\/\/www.mhlw.go.jp\/stf\/seisakunitsuite\/bunya\/0000082537.html\" target=\"_blank\" rel=\"noopener\">\u539a\u751f\u52b4\u50cd\u7701\uff5c\u767b\u9332\u8ca9\u58f2\u8005\u8a66\u9a13\u554f\u984c\u4f5c\u6210\u306b\u95a2\u3059\u308b\u624b\u5f15\u304d\uff08\u4ee4\u548c\uff17\u5e74\uff14\u6708\uff09<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.pmda.go.jp\/\" target=\"_blank\" rel=\"noopener\">PMDA\uff08\u533b\u85ac\u54c1\u533b\u7642\u6a5f\u5668\u7dcf\u5408\u6a5f\u69cb\uff09<\/a><\/li>\n\n\n\n<li><a href=\"https:\/\/www.msdmanuals.com\/ja-jp\/home\" target=\"_blank\" rel=\"noopener\">MSD\u30de\u30cb\u30e5\u30a2\u30eb\u5bb6\u5ead\u7248\uff08\u300c\u85ac\u7269\u52d5\u614b\u300d\u3092\u691c\u7d22\uff09<\/a><\/li>\n<\/ul>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"\u4ee3\u8b1d\u30fb\u6392\u6cc4\u30fb\u8840\u4e2d\u6fc3\u5ea6\uff5c\u85ac\u304c\u4f53\u5185\u3067\u305f\u3069\u308b\u30d7\u30ed\u30bb\u30b9\" width=\"500\" height=\"281\" src=\"https:\/\/www.youtube.com\/embed\/lKXumexfy1M?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><\/figure>\n\n\n\n<p>\u203b\u89e3\u8aac\u97f3\u58f0\u306fAI\u30c4\u30fc\u30eb\u300cNotebookLM\u300d\u3067\u4f5c\u6210\u3057\u3066\u3044\u307e\u3059\u3002\u8aad\u307f\u4e0a\u3052\u306e\u4e0d\u81ea\u7136\u3055\u304c\u6b8b\u308b\u90e8\u5206\u3082\u3042\u308a\u307e\u3059\u304c\u3001\u5185\u5bb9\u306e\u7406\u89e3\u3092\u52a9\u3051\u308b\u3082\u306e\u3068\u3057\u3066\u8f09\u305b\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p>\u516c\u958b\u65e5\uff1a2025\u5e747\u670820\u65e5<br>\n\u6700\u7d42\u66f4\u65b0\u65e5\uff1a2026\u5e744\u670824\u65e5<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u300c\u540c\u3058\u85ac\u3092\u98f2\u3093\u3067\u3082\u4eba\u306b\u3088\u3063\u3066\u52b9\u304d\u65b9\u304c\u9055\u3046\u300d\u300c\u809d\u81d3\u3084\u814e\u81d3\u304c\u60aa\u3044\u3068\u85ac\u306b\u6ce8\u610f\u304c\u5fc5\u8981\u300d\u2014\u2014\u305d\u306e\u7406\u7531\u306f\u3001\u85ac\u304c\u4f53\u5185\u3067\u305f\u3069\u308b\u30d7\u30ed\u30bb\u30b9\u3068\u6df1\u304f\u95a2\u4fc2\u3057\u3066\u3044\u307e\u3059\u3002 \u3053\u306e\u8a18\u4e8b\u3067\u306f\u767b\u9332\u8ca9\u58f2\u8005\u8a66\u9a13\u306e\u5185\u5bb9\u3092\u30d9\u30fc\u30b9\u306b\u3001\u85ac\u306e\u4ee3\u8b1d\u30fb\u6392\u6cc4\u30fb\u8840\u4e2d\u6fc3\u5ea6\u306e\u3057\u304f\u307f\u3092 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":706,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jinr_url_youtube":"","_jinr_pip_youtube":false,"_jinr_time_youtube":"","_jinr_thumb_youtube":"","_jinr_media_youtube":"","_jinr_category_edit":false,"_jinr_category":"","_jinr_title_display":false,"_jinr_snsbutton_display":false,"_jinr_ads_display":false,"_jinr_thumbnail_display":false,"_jinr_profile_display":false,"_jinr_representations_display":false,"_jinr_relatedpost_display":false,"_jinr_sidebar1col_display":false,"_jinr_sidebar2col_display":false,"_jinr_seotitle_display":"","_jinr_description_display":"","_jinr_keyword_display":"\u85ac\u306e\u4ee3\u8b1d\u3001\u85ac\u306e\u6392\u6cc4\u3001\u8840\u4e2d\u6fc3\u5ea6\u3001\u809d\u521d\u56de\u901a\u904e\u52b9\u679c\u3001\u6cbb\u7642\u57df\u3001\u6709\u52b9\u57df\u3001\u4e2d\u6bd2\u57df\u3001\u6700\u4f4e\u6709\u52b9\u6fc3\u5ea6\u3001\u814e\u6a5f\u80fd\u3001\u809d\u6a5f\u80fd\u3001\u85ac\u306e\u4f53\u5185\u52d5\u614b\u3001\u8840\u6f3f\u30bf\u30f3\u30d1\u30af\u7d50\u5408\u3001\u85ac\u306e\u526f\u4f5c\u7528\u3001\u85ac\u306e\u52b9\u679c\u3001\u4ee3\u8b1d\u9175\u7d20\u3001\u30a2\u30eb\u30d6\u30df\u30f3\u3001\u9580\u8108\u3001\u809d\u81d3\u3067\u306e\u4ee3\u8b1d\u3001\u5c3f\u4e2d\u6392\u6cc4\u3001\u80c6\u6c41\u6392\u6cc4\u3001\u80ba\u6392\u6cc4\u3001first-pass effect\u3001\u85ac\u306e\u5438\u53ce\u3068\u6392\u6cc4\u3001\u85ac\u306e\u8840\u4e2d\u6fc3\u5ea6\u7ba1\u7406\u3001\u85ac\u306e\u5faa\u74b0\u3001\u85ac\u304c\u4f53\u5185\u3092\u5de1\u308b\u904e\u7a0b\u3001\u85ac\u306e\u5438\u53ce\u304b\u3089\u6392\u6cc4\u307e\u3067\u306e\u6d41\u308c\u3001\u85ac\u304c\u4ee3\u8b1d\u3055\u308c\u308b\u4ed5\u7d44\u307f\u3001\u809d\u81d3\u3067\u4ee3\u8b1d\u3055\u308c\u308b\u85ac\u306e\u7279\u5fb4\u3001\u814e\u81d3\u304b\u3089\u6392\u6cc4\u3055\u308c\u308b\u85ac\u3001\u8840\u4e2d\u6fc3\u5ea6\u304c\u85ac\u306e\u52b9\u304d\u65b9\u306b\u4e0e\u3048\u308b\u5f71\u97ff\u3001\u809d\u521d\u56de\u901a\u904e\u52b9\u679c\u3067\u52b9\u679c\u304c\u843d\u3061\u308b\u85ac\u3001\u8840\u4e2d\u6fc3\u5ea6\u3068\u526f\u4f5c\u7528\u306e\u95a2\u4fc2\u3001\u6700\u4f4e\u6709\u52b9\u6fc3\u5ea6\u3092\u4e0b\u56de\u308b\u3068\u52b9\u679c\u304c\u306a\u3044\u7406\u7531\u3001\u85ac\u306e\u6cbb\u7642\u57df\u3068\u306f\u4f55\u304b\u3001\u4e2d\u6bd2\u57df\u306b\u9054\u3059\u308b\u3068\u8d77\u3053\u308b\u526f\u4f5c\u7528\u3001\u809d\u6a5f\u80fd\u304c\u4f4e\u3044\u4eba\u306b\u4f7f\u3046\u85ac\u306e\u6ce8\u610f\u70b9\u3001\u814e\u6a5f\u80fd\u304c\u60aa\u3044\u4eba\u306b\u85ac\u3092\u4f7f\u3046\u6642\u306e\u30ea\u30b9\u30af\u3001\u8840\u4e2d\u6fc3\u5ea6\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u304c\u5fc5\u8981\u306a\u85ac\u3001\u85ac\u306e\u4ee3\u8b1d\u7269\u306e\u6392\u6cc4\u7d4c\u8def\u3001\u85ac\u306e\u6709\u52b9\u6fc3\u5ea6\u3092\u7dad\u6301\u3059\u308b\u65b9\u6cd5\u3001\u30a2\u30eb\u30d6\u30df\u30f3\u3068\u306e\u7d50\u5408\u3067\u5909\u5316\u3059\u308b\u85ac\u306e\u4f5c\u7528","_jinr_hastag_display":"","_jinr_canonical_display":"","_jinr_noindex_display":false,"_jinr_paidpost":false,"_jinr_paidpost_product_id":"","_jinr_headtag_article":"","_jinr_ogp_image_url":"","_jinr_last_featured_id":0,"footnotes":""},"categories":[11],"tags":[23,12,13,14],"class_list":["post-699","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-11","tag-23","tag-12","tag-13","tag-14"],"views":"6","_links":{"self":[{"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=\/wp\/v2\/posts\/699","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=699"}],"version-history":[{"count":15,"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=\/wp\/v2\/posts\/699\/revisions"}],"predecessor-version":[{"id":3300,"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=\/wp\/v2\/posts\/699\/revisions\/3300"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=\/wp\/v2\/media\/706"}],"wp:attachment":[{"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=699"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=699"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/cocorokaradamegulu.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=699"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}